Maternal use of Loratadine during pregnancy and risk of hypospadias in offspring
نویسندگان
چکیده
منابع مشابه
Maternal use of Loratadine during pregnancy and risk of hypospadias in offspring
To examine the risk of hypospadias after exposure to loratadine and other antihistamines during pregnancy, we conducted a population-based case-control study in four Danish counties, which account for 30% of the Danish population (approximately 1.6 M). We obtained data on maternal use of antihistamines from prescription databases, and data on birth outcomes from the Danish Medical Birth Registr...
متن کاملNo increased risk of infant hypospadias after maternal use of loratadine in early pregnancy
The original report published in 2001 on a possible association between maternal use of loratadine and an increased risk of infant hypospadias, based on data in the Swedish Medical Birth Register 1995-2001, has been followed up by continued surveillance in the same register. The original "signal" was based on 15 infants with hypospadias among 2780 loratadine-exposed infants born, representing a...
متن کاملMaternal Pregnancy Levels of Polychlorinated Biphenyls and Risk of Hypospadias and Cryptorchidism in Male Offspring
BACKGROUND The etiologies of the male urogenital anomalies cryptorchidism and hypospadias are poorly understood. It has been suggested, however, that in utero hormone levels may be related to risk. Endocrine-disrupting chemicals, including polychlorinated biphenyl (PCB) compounds, may alter hormone levels and thereby affect the fetus. OBJECTIVES To examine whether in utero PCB exposure is rel...
متن کاملMaternal tobacco, cannabis and alcohol use during pregnancy and risk of adolescent psychotic symptoms in offspring.
BACKGROUND Adverse effects of maternal substance use during pregnancy on fetal development may increase risk of psychopathology. AIMS To examine whether maternal use of tobacco, cannabis or alcohol during pregnancy increases risk of offspring psychotic symptoms. METHOD A longitudinal study of 6356 adolescents, age 12, who completed a semi-structured interview for psychotic symptoms in the A...
متن کاملMaternal tobacco use during pregnancy and risk of congenital heart defects in offspring: a systematic review
Background Numerous human studies have investigated potential teratogenic effects of maternal smoking during pregnancy, with conflicting findings [1,2]. One of the most common birth malformations is congenital heart defect (CHD) with a prevalence of around 1% of live births [3,4]. More specifically, several studies indicate that maternal tobacco use is related with increased risk of CHD, wherea...
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ژورنال
عنوان ژورنال: International Journal of Medical Sciences
سال: 2006
ISSN: 1449-1907
DOI: 10.7150/ijms.3.21